Author

Ayub Boulos

Broad InstituteORCID 0000-0002-5329-0895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron HeldiD· 1 shared Amir EdeniD· 1 shared Ana Rita Agra de Almeida QuadrosiD· 1 shared Aya Muharram· 1 shared Benjamin P. KleinstiveriD· 1 shared Benjamin WymanniD· 1 shared Brian J. WaingeriD· 1 shared C. Alves· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Aaron HeldORCID

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2 papers

Recent·Most cited

Statins and genetic inhibition of the mevalonate pathway activate an ATF3-STMN2 regenerative program

Matthew Nolan, Sandeep Aryal, I. Sandra Ndayambaje, Maize Cao, Peyton Lee, Moriah J. Hovde, Shuqi Yun, Josette J Wlaschin, Aaron Held, Hortense D. A. M. Beaussant, Benjamin Wymann, Chao-Zong Lee, Su Min Lim, Xin Jiang, Nandini Ramesh, , Clotilde Lagier‐Tourenne

The paper shows statins and mevalonate pathway inhibition increase STMN2 and ATF3, promoting neuronal regeneration in neurodegenerative disease.

bioRxiv · Feb 24, 2026 · PreprintNeuroscience

A Novel Role for Nucleolin in Splice Site Selection

Kinneret Shefer, Ayub Boulos, Valer Gotea, Maram Arafat, Yair Ben-Chaim, Aya Muharram, Sara Isaac, Amir Eden, Joseph M. Sperling, Laura L. Elnitski, Ruth Sperling

This study identifies nucleolin as a novel regulator of splice site selection by directly interacting with initiator-tRNA, preventing latent splicing that would generate defective mRNAs.

RNA Biology · Feb 27, 2022Peer-reviewedGenomics