Author

Giovanna Giovinazzo

Spanish National Centre for Cardiovascular ResearchORCID 0000-0002-5391-0441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Arturo Londoño‐VallejoiD· 2 shared Carlota Sánchez-Ferrer· 2 shared Charles FouilladeiD· 2 shared Christelle CayrouiD· 2 shared Dmitri ChurikoviD· 2 shared Elisa Santos· 2 shared Emmanuelle JosseliniD· 2 shared Éric GilsoniD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Arturo Londoño‐VallejoORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

P53 and BCL-2 family proteins PUMA and NOXA define competitive fitness in Pluripotent Cells

Jose Antonio Valverde-Lopez, Lin Li-Bao, Covadonga Díaz-Díaz, Rocío Sierra, Elisa Santos, Giovanna Giovinazzo, Miguel Torres

The paper identifies P53 and its targets PUMA and NOXA as regulators of competitive fitness in pluripotent cells through mitochondrial regulation.

bioRxiv · May 21, 2023 · PreprintDevelopmental Biology

Induction of telomerase in p21-positive cells counteracts capillaries rarefaction in aging mice lung

Larissa Lipskaia, Marielle Breau, Christelle Cayrou, Dmitri Churikov, Laura Braud, Charles Fouillade, Sandra Curras-Alonso, Serge Bauwens, Frédéric Jourquin, Frédéric FIORE, Rémy Castellano, Emmanuelle Josselin, Carlota Sánchez-Ferrer, Giovanna Giovinazzo, Éric Gilson, , Vincent Géli

The paper shows that inducing telomerase in p21-positive cells in aging mice lungs reduces capillary rarefaction and improves lung function by promoting microvasculature regeneration.

bioRxiv · Oct 27, 2022 · PreprintMolecular Biology

Pluripotency factors regulate the onset of Hox cluster activation in the early embryo

Elena Lopez-Jimenez, Julio Sainz de Aja, Claudio Badía-Careaga, Antonio Barral, Isabel Rollán, Raquel Rouco, Elisa Santos, María Tiana, Jesús Victorino, Héctor Sánchez-Iranzo, Rafael D. Acemel, Carlos Torroja, Javier Adan, Eduardo Andrés‐León, José Luis Gómez-Skármeta, , Miguel Manzanares

This study shows pluripotency factors like OCT4 and NANOG initially repress and later enable activation of lineage specifiers, including the HoxB cluster, during early embryonic development.

Science Advances · Jul 15, 2022Peer-reviewedDevelopmental Biology

Telomerase Prevents Emphysema in Old Mice by Sustaining Subpopulations of Endothelial and AT2 Cells

Marielle Breau, Christelle Cayrou, Dmitri Churikov, Charles Fouillade, Sandra Curras-Alonso, Serge Bauwens, Frédéric Jourquin, Laura Braud, Frédéric FIORE, Rémy Castellano, Emmanuelle Josselin, Carlota Sánchez-Ferrer, Giovanna Giovinazzo, Éric Gilson, Ignacio Flores, , Vincent Géli

This study shows that telomerase expression in old mice prevents emphysema by maintaining endothelial and AT2 cell populations through increased proliferation.

bioRxiv · Jan 7, 2021 · PreprintMolecular Biology