Author

Zhijie Li

Chinese Academy of SciencesORCID 0000-0002-5445-7976Unclaimed ORCID profile · follow to get notified of new preprints

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Zhijie Li2 papers · Xiamen University

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Hui YangiD· 2 shared Bingbing HeiD· 1 shared C. Frank BennettiD· 1 shared Chixiang LuiD· 1 shared Chunlong XuiD· 1 shared Di CuiiD· 1 shared Gu Chen· 1 shared Haibo Jiang· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Hui YangORCID

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2 papers

Recent·Most cited

Automated Multimodal Correlative Registration for Organelle-Specific Molecular Imaging

Chixiang Lu, Kaiqiang ZHAO, Di Cui, Gu Chen, Qian Yang, Hui Yang, Murong Zhao, Kaiyun Song, Mehran Nikan, Zhijie Li, Shanchao Zhao, Jinpeng Cen, Xincheng Qiu, Stephen G. Young, C. Frank Bennett, , Haibo Jiang

The paper introduces an automated AI pipeline for correlating chemical and ultrastructural images to enable organelle-specific molecular imaging in cells and tissues.

bioRxiv · May 4, 2026 · PreprintBioinformatics

Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver

Bingbing He, Wenbo Peng, Jia Huang, Hang Zhang, Yingsi Zhou, Xiali Yang, Jing Liu, Zhijie Li, Chunlong Xu, Mingxing Xue, Hui Yang, Pengyu Huang

This study demonstrates the use of CasRx-mediated RNA knockdown to modulate metabolic genes in mouse liver, showing efficient and reversible reduction of PCSK9 and cholesterol levels.

Protein & Cell · Mar 18, 2020Peer-reviewedGenomics