Kai Papenfort

The ArcZ small RNA activates SlyA production to control contact-dependent antibacterial killing and diffusible antifungal activity in Dickeya solani

The paper identifies an sRNA regulatory cascade in Dickeya solani that controls both antifungal and antibacterial activities by activating SlyA translation.

Host infection selects for sRNA variants that drive bacterial social cheating

The paper shows that single-nucleotide mutations in the sRNA ArcZ of Dickeya solani generate social cheater variants during potato infection, which exploit a shared metabolic benefit without contributing to it.

A nucleic acid host factor enables optimal phage replication in Escherichia coli

The paper shows that T2 phage uses the host sRNA ArcZ to stabilize its own transcript and inhibit a bacterial restriction system.

A 3UTR-derived small RNA modulates the life-cycle of the cholera toxin-encoding filamentous phage, CTXphi

The paper identifies and characterizes CisR, a small RNA that inhibits CTXφ phage production by repressing cep mRNA through Hfq-dependent base-pairing, linking phage activation to cell density and nutrient availability in V. cholerae.

The transcription factor Vca0578 (DsvR) mediated expression of ZapC is required to promote cell division during lytic transglycosylase insufficiency in Vibrio cholerae

Quorum sensing employs a dual regulatory mechanism to repress T3SS gene expression

This study identifies a dual regulatory mechanism by LuxR in Vibrio campbellii that represses T3SS gene expression through transcriptional and post-translational repression of ExsA activity.

Phage-phage competition and biofilms reduce the efficacy of a combination of two virulent bacteriophages against Pseudomonas aeruginosa

This study investigates how phage-phage competition and biofilm formation affect the efficacy of a two-phage combination against Pseudomonas aeruginosa in vitro.

MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

This study identifies MftG as a mycofactocin dehydrogenase essential for ethanol metabolism in mycobacteria by linking mycofactocin oxidation to respiration.

ChimericFragments: Computation, analysis, and visualization of global RNA networks

ChimericFragments identifies RNA-RNA interactions from chimeric RNA-seq data and outperforms existing methods.