Xueshu Xie

This study shows that amyloid β accelerates age-related protein insolubility in C. elegans and links this process to neurodegenerative and age-related diseases through proteomics and GWAS.

This study identifies high stoichiometry lysine succinylation sites in mouse liver, showing their functional role in urea cycle regulation and ammonia metabolism through SIRT5.

The paper introduces a method to quantify lysine and arginine PTMs in NASH using mass spectrometry and applies it to mouse liver lysates, finding altered methylation and acetylation in NASH.