This paper introduces a bioengineered stem cell organoid system to model human neural crest development, showing it recapitulates key developmental dynamics and can be used for cross-species validation.

bioRxiv · May 6, 2026 · PreprintDevelopmental Biology

Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In vitro

Pacharaporn Suklai, Taylor F. Minckley, Cathleen Hagemann, Karolina Faber, Rosalind Norkett, Ludovica Guetta, Kelly O’Toole, Bethany Geary, Michael J. Devine, Andrea Serio

The paper introduces an open platform for creating functional cortical circuits using iPSC-derived neurons, enabling controlled network assembly and analysis of synaptic activity and connectivity.

Advanced Healthcare Materials · Oct 24, 2025Peer-reviewedNeuroscience

The V-ATPase/ATG16L1 axis is controlled by the V1H subunit

Lewis Timimi, Antoni G. Wrobel, George N. Chiduza, Sarah Maslen, Antonio Torres-Méndez, Beatriz Montaner, Colin T. Davis, Taylor F. Minckley, Katriona L. Hole, Andrea Serio, Michael J. Devine, Mark J. Skehel, John L. Rubinstein, Anne Schreiber, Rupert C. L. Beale

This paper identifies the V1H subunit of V-ATPase as a regulator of ATG16L1 recruitment in response to pH gradient disruption, linking V-ATPase function to autophagy activation.

Molecular Cell · Jul 31, 2024Peer-reviewedMolecular Biology