Michael J. Devine

The paper tracks mitochondrial gene expression in live neurons using nanotweezers and finds downregulation of MT-ND1 and MT-ATP6 after exposure to α-synuclein aggregates.

The study shows MitoTracker transfers from astrocytes to neurons without requiring mitochondrial transfer.

The paper introduces an open platform for creating functional cortical circuits using iPSC-derived neurons, enabling controlled network assembly and analysis of synaptic activity and connectivity.

The paper shows that ER morphology affects neuronal bursting by controlling Ca2+ refill rates, linking ER structure to neuronal activity and neurodegeneration.

This paper identifies the V1H subunit of V-ATPase as a regulator of ATG16L1 recruitment in response to pH gradient disruption, linking V-ATPase function to autophagy activation.

The paper analyzes mitochondria in the Drosophila connectome, showing variations in size, location, and appearance across cell types and brain regions.