Author

Jian‐Fei Lu

Shanghai Jiao Tong UniversityORCID 0000-0002-5807-6433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Tian‐Le XuiD· 2 shared Di-Shi LiuiD· 1 shared Guofen MaiD· 1 shared Haibo ShiiD· 1 shared Han-Wei Liu· 1 shared Iva PritišanaciD· 1 shared Jaepyo JeoniD· 1 shared Julie Deborah Forman-KayiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Tian‐Le XuORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Glutamate as a co-agonist for acid-sensing ion channels to aggravate ischemic brain damage

Ke Lai, Iva Pritišanac, Zhen-Qi Liu, Han-Wei Liu, Li-Na Gong, Mingxian Li, Jian‐Fei Lu, Xin Qi, Tian‐Le Xu, Julie Deborah Forman-Kay, Haibo Shi, Lu‐Yang Wang, Shankai Yin

This study identifies glutamate as a co-agonist for acid-sensing ion channels (ASICs) that worsens ischemic brain damage, and presents a small molecule inhibitor that targets this interaction without affecting NMDARs.

bioRxiv · Feb 17, 2024 · PreprintNeuroscience

Phosphatidylserine controls synaptic targeting and membrane stability of ASIC1a

Di-Shi Liu, Xing-Lei Song, Ming‐Gang Liu, Jian‐Fei Lu, Yu Huang, Jaepyo Jeon, Guofen Ma, Yong Li, Lucas D. Pozzo‐Miller, Michael X. Zhu, Tian‐Le Xu

This study identifies phosphatidylserine (PS) as a critical lipid for ASIC1a synaptic targeting and function through electrostatic interactions.

bioRxiv · Sep 29, 2022 · PreprintNeuroscience