ImmunologybioRxivPreprint
Ketone ester supplementation reduces age-associated B cell activation in aged mice without impairing antibody responses
Ariel Floro, Ritesh Tiwari, Mitsunori Nomura…·Eric M. Verdin
DOI 10.64898/2026.04.20.718782
Author
Rebeccah R. Riley
Buck Institute for Research on AgingORCID 0000-0002-5870-6837Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2023-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship7 papers
Recent·Most cited
- ImmunologyAging CellPeer-reviewed
Multi-omics Analysis of Human Blood Cells Reveals Unique Features of Age-associated Type2 CD8 Memory T cells
Hiroyuki Matsui, Marlene Cervantes, Mir Mubashir Khalid…·Eric Verdin
The paper identifies age-associated Th2-like CD8 memory T cells in human blood and links their accumulation to health conditions like asthma and diabetes.
1 citation - Cell BiologybioRxivPreprint
Multiplexed Targeted iprm-PASEF Assays for MALDI Mass Spectrometry Imaging of Lipids, NAD+ 2 , and Related Metabolites in CD38 Knockout Mice
Charles A. Schurman, Joanna Bons, Prasanna Vadhana Ashok Kumaar…·Birgit Schilling
The paper introduces iprm-PASEF, a targeted MSI method, to identify and quantify metabolites and lipids in CD38 knockout mice, showing increased NAD+ and decreased ADPR.
6 citations - Molecular BiologyNature MetabolismPeer-reviewed
Regulation of urea cycle by reversible high stoichiometry lysine succinylation
Ran Zhang, Jingqi Fang, Xueshu Xie…·Eric M. Verdin
This study identifies high stoichiometry lysine succinylation sites in mouse liver, showing their functional role in urea cycle regulation and ammonia metabolism through SIRT5.
28 citationstop 2% - Molecular BiologybioRxivPreprint
Chronically disrupted sleep induces senescence in the visceral adipose tissue of C57BL/6J mice
Daria Timonina, Genesis Vega Hormazabal, Indra Heckenbach…·Eric M. Verdin
This study shows that sleep disruption in mice increases cellular senescence in visceral adipose tissue, leading to oxidative stress and DNA damage, which may accelerate aging and age-related diseases.
DOI 10.1101/2023.10.17.562803 - Developmental BiologyiSciencePeer-reviewed
CD38 regulates ovarian function and fecundity via NAD+ metabolism
Rosalba Perrone, Prasanna Vadhana Ashok Kumaar, Lauren Haky…·Eric M. Verdin
This study shows CD38 loss increases ovarian NAD+ levels and fecundity in young mice but not in older mice.
30 citationstop 2% - GenomicsbioRxivPreprint
Development of a novel epigenetic clock resistant to changes in immune cell composition
Alan Tomusiak, Ariel Floro, Ritesh Tiwari…·Eric M. Verdin
The paper develops a novel epigenetic clock, IntrinClock, that measures age-related changes independent of immune cell composition, showing age reversal in reprogramming.
14 citations