Molly Strom

The paper introduces BRISC, a method to map neural circuits in the mouse brain using barcoded rabies viruses, identifying synaptic connections in the primary visual cortex.

This study identifies TRPML1 loss as a cause of lysosomal calcium failure and astrocyte dysfunction in Alzheimer's Disease, showing that restoring TRPML1 can prevent disease progression.

This paper develops a stable reporter coronavirus for studying transcriptional responses in infected and bystander cells, finding that infection primarily triggers inflammatory rather than interferon-mediated host responses.

The study shows MitoTracker transfers from astrocytes to neurons without requiring mitochondrial transfer.

This study shows that a modified Ascl1 variant, Ascl1SA6, can reprogram glial cells into interneurons that resemble canonical cortical interneurons when combined with Dlx2, improving their laminar positioning.

The paper shows how hunger and estrous state interact in the MPOA to regulate infant-directed aggression in mice.

This study identifies lactate as a tumor-secreted metabolite that inhibits B cell chemotaxis and TLS formation in TNBC by disrupting mitochondrial metabolism.

This paper introduces a pooled prime editing platform in haploid human cells to assess the functional effects of genetic variants, showing high accuracy in identifying loss-of-function variants and pathogenic non-coding variants.

The paper introduces a deep learning algorithm for automated 3D detection of neuronal somata in whole mouse brain images, demonstrating its effectiveness on fluorescently labeled cell populations.