Author

Xinzhu Zhou

University of California San DiegoORCID 0000-0002-6432-0033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Abraham A. PalmeriD· 1 shared Amir Motamedi· 1 shared Andrew K. ShiauiD· 1 shared Apurva S. ChitreiD· 1 shared Bing ReniD· 1 shared Celine L. St. PierreiD· 1 shared Charles T. Yokoyama· 1 shared Daisuke TsuboiiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperGenetics

Abraham A. PalmerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

KCNQ2/3 Regulates the Synaptic Remodeling Associated with Drug Seeking in Addiction

Xinzhu Zhou, Xinjian Zhang, Yasuhiro Funahashi, Daisuke Tsuboi, Tetsuya Takano, Hisayoshi Kubota, Charles T. Yokoyama, Toshitaka Nabeshima, Kiyofumi Yamada, Kozo Kaibuchi, Taku Nagai

This study identifies KCNQ2/3 potassium channels as regulators of synaptic remodeling during withdrawal, showing their activation can suppress cocaine-seeking behavior.

bioRxiv · Jun 16, 2026 · PreprintNeuroscience

SnapATAC: A Comprehensive Analysis Package for Single Cell ATAC-seq

Rongxin Fang, Sebastian Preißl, Yang Li, Xiaomeng Hou, Jacinta D. Lucero, Xinxin Wang, Amir Motamedi, Andrew K. Shiau, Xinzhu Zhou, Fangming Xie, Eran A. Mukamel, Kai Zhang, Yanxiao Zhang, M. Margarita Behrens, Joseph R. Ecker, Bing Ren

SnapATAC is a software package for analyzing scATAC-seq data, revealing regulatory elements and transcriptional regulators in mouse brain cells.

Nature Communications · Feb 26, 2021Peer-reviewedBioinformatics

Genome-wide association study in two cohorts from a multi-generational mouse advanced intercross line highlights the difficulty of replication

Xinzhu Zhou, Celine L. St. Pierre, Natalia M. Gonzales, Jennifer Zou, Riyan Cheng, Apurva S. Chitre, Greta Sokoloff, Abraham A. Palmer

This study investigates replication challenges in GWAS using two mouse cohorts, finding limited replication success despite similar sample sizes and population origins.

G3 Genes Genomes Genetics · Jan 23, 2020Peer-reviewedGenetics