Mauro Martins Teixeira

CORONAVIRUS INFECTION ACCELERATES EXPERIMENTAL OSTEOPOROSIS THROUGH THE ACTIVATION OF OSTEOCLASTS

This study shows that coronavirus infection accelerates bone loss in mice with osteoporosis by increasing osteoclast activity and inflammation.

Comparison of oviposition and adult trapping to monitor wMel introgression for Wolbachia-based vector control

This study compares ovitrap and BG-trap methods for monitoring Wolbachia introgression in Aedes aegypti mosquitoes, finding ovitraps provide reliable and cost-effective estimates.

PI3Kγ pathway contributes to neuroinflammation and neuronal death induced by Zika virus infection

This study investigates the role of the PI3Kγ pathway in ZIKV-induced neuroinflammation and neuronal death, finding that its inhibition reduces viral replication and neuroinflammatory responses.

Activation of bradykinin receptor B1 promotes desensitization of CXCR2 in neutrophils during severe sepsis and contributes to disease progression in mice.

This study shows that BDKRB1 activation worsens sepsis by impairing neutrophil migration and CXCR2 function, and inhibiting BDKRB1 improves survival and bacterial clearance in mice.

P2Y12-P-Selectin Mediated Platelet Activation Drives Dengue-Associated Thrombocytopenia

This study shows DENV causes thrombocytopenia through impaired megakaryopoiesis and P-selectin-mediated platelet activation, with potential therapeutic targets identified.

Cyclodextrin-Based Delivery of the Annexin A1 Mimetic Peptide Ac2-26 Enhances Anti-Inflammatory Effects and PreventsDengue-Induced Lethality in Combination with AntiviralTherapy

This study shows that cyclodextrin-based delivery of the anti-inflammatory peptide Ac2-26 improves survival in dengue-infected mice when combined with antiviral therapy.

Profile of the B cell receptor repertoire and antibody responses upon 17DD-YF vaccine boosting

This study examines the B cell receptor repertoire and antibody responses after 17DD-YF vaccine boosting, finding a transient antibody response with limited neutralization capacity and rapid clonal expansion of IgA and IgG isotypes.

Neuropsychiatric sequelae in an experimental model of post-COVID syndrome in mice

This study establishes a sex-dependent mouse model of post-COVID syndrome, showing neuropsychiatric and musculoskeletal complications in females that are prevented by ovariectomy.

Broad-Spectrum Antiviral Efficacy of 7-Deaza-7-Fluoro-2'-C-Methyladenosine Against Multiple Coronaviruses In Vitro and In Vivo

This study evaluates DFMA's antiviral efficacy against multiple coronaviruses in vitro and in vivo, showing significant reductions in viral load and inflammation across different models.

Prevalence of bacterial pathogens and potential role in COVID-19 severity in patients admitted to intensive care units in Brazil

The paper identifies prevalent respiratory, nosocomial, and bacterial pathogens in Brazilian COVID-19 ICU patients and correlates their virulence factors with disease severity.