Author

Jason Tse

Scripps Research InstituteORCID 0000-0002-6958-0256Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

Antara ChakravartyiD· 1 shared Benjamin F. CravattiD· 1 shared Bruno N. MelilloiD· 1 shared David R. LiuiD· 1 shared Eric S. FischeriD· 1 shared Evert NjomeniD· 1 shared Gene Wei-Ming YeoiD· 1 shared Guangyan Du· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Antara ChakravartyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ESCAPE: assigning site-specific activity to covalent ligands in cells by prime editing

Jason Tse, William R. Brothers, Rachel E. Hayward, Sabrina Barbas, Kai Sheng, Kathryn R. Spencer, Kristen E. DeMeester, Evert Njomen, James R. Williamson, David R. Liu, Bruno N. Melillo, Gene Wei-Ming Yeo, Benjamin F. Cravatt, Haoxin Li

ESCAPE identifies covalent ligand-protein interactions by using prime editing to disrupt cysteine residues and assesses their impact on cellular phenotypes.

bioRxiv · Jul 29, 2026 · PreprintBiochemistry

Discovery of Potent Degraders of the Dengue Virus Envelope Protein

Zhengnian Li, Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang, Inchul You, Hong Yue, Katherine A. Donovan, Guangyan Du, Jianwei Che, Jason Tse, Isaac Che, Wenchao Lu, Eric S. Fischer, , Priscilla L. Yang

This study develops small molecule degraders of the dengue virus envelope protein, demonstrating their ability to induce proteosome-mediated degradation and providing a foundation for antiviral drug development.

Advanced Science · Aug 15, 2024Peer-reviewedBiochemistry