Author

Han‐Yuan Liu

Amgen (United States)ORCID 0000-0002-9398-6969Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

Alex Golkar· 1 shared Alex Rosa CamposiD· 1 shared Amber D. Senese· 1 shared Amit VaishiD· 1 shared Anastasia Velentza· 1 shared Andrew Burritt· 1 shared Animesh Chandra RoyiD· 1 shared Antara ChakravartyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Alex Golkar

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Discovery of a VHL molecular glue degrader of GEMIN3 by Picowell RNA-seq

Jonathan W. Bushman, Weixian Deng, Kusal T. G. Samarasinghe, Han‐Yuan Liu, Shiqian Li, Amit Vaish, Alex Golkar, Shu Ou, Jinwoo Ahn, Rajesh K. Harijan, Han Han, Tomas Duffy, Elliot Imler, Judy Qiju Wu, Reneé Rawson, , Patrick Ryan Potts

The paper discovers a VHL molecular glue degrader of GEMIN3 using Picowell RNA-seq screening, showing how it targets GEMIN3 for degradation through ternary complex formation.

bioRxiv · Mar 19, 2025 · PreprintBiochemistry

Discovery of Potent Degraders of the Dengue Virus Envelope Protein

Zhengnian Li, Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang, Inchul You, Hong Yue, Katherine A. Donovan, Guangyan Du, Jianwei Che, Jason Tse, Isaac Che, Wenchao Lu, Eric S. Fischer, , Priscilla L. Yang

This study develops small molecule degraders of the dengue virus envelope protein, demonstrating their ability to induce proteosome-mediated degradation and providing a foundation for antiviral drug development.

Advanced Science · Aug 15, 2024Peer-reviewedBiochemistry