Author

Inchul You

Stanford Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Organism:virus· 1

Frequent Co-Authors

Nathanael S. GrayiD· 4 shared Eric S. FischeriD· 3 shared Katherine A. DonovaniD· 3 shared Stephen M. HinshawiD· 2 shared Woong Sub ByuniD· 2 shared Zhengnian LiiD· 2 shared Zixuan JiangiD· 2 shared Antara ChakravartyiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersBiochemistry

Nathanael S. GrayORCID

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Author profile →

4 papers

Recent·Most cited

Charged Molecular Glue Discovery Enabled by Targeted Degron Display

Zhe Zhuang, Woong Sub Byun, Jakub Chrustowicz, Zuzanna Kozicka, Veronica L. Li, Dinah M. Abeja, Katherine A. Donovan, Sara Sepic, Inchul You, Mikolaj Michal Slabicki, Eric S. Fischer, Stephen M. Hinshaw, Benjamin L. Ebert, Brenda Arlene Schulman, Nathanael S. Gray

The paper discovers a charged molecular glue, c-Glue, through targeted degron display, enabling the development of Molecular Glue Degraders (MGDs) for protein degradation.

Nature Chemical Biology · Apr 6, 2026Peer-reviewedBiochemistry

Discovery of CRBN-dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial Library

Hlib Razumkov, Zixuan Jiang, Kheewoong Baek, Inchul You, Qixiang Geng, Katherine A. Donovan, Michelle T. Tang, Rebecca J. Metivier, Nada Mageed, Pooreum Seo, Zhengnian Li, Woong Sub Byun, Stephen M. Hinshaw, Roman C. Sarott, Eric S. Fischer, Nathanael S. Gray

The paper identifies CRBN-dependent WEE1 molecular glue degraders through combinatorial library screening and medicinal chemistry, providing structural insights into kinase selectivity.

Journal of the American Chemical Society · Nov 5, 2024Peer-reviewedMolecular Biology

Discovery of Potent Degraders of the Dengue Virus Envelope Protein

Zhengnian Li, Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang, Inchul You, Hong Yue, Katherine A. Donovan, Guangyan Du, Jianwei Che, Jason Tse, Isaac Che, Wenchao Lu, Eric S. Fischer, , Priscilla L. Yang

This study develops small molecule degraders of the dengue virus envelope protein, demonstrating their ability to induce proteosome-mediated degradation and providing a foundation for antiviral drug development.

Advanced Science · Aug 15, 2024Peer-reviewedBiochemistry

Down-regulation of AKT proteins slows the growth of mutant-KRAS pancreatic tumors

Chuankai Chen, Yaping Jiang, Inchul You, Nathanael S. Gray, Richard Z. Lin

This study shows that down-regulating AKT proteins slows mutant-KRAS pancreatic tumor growth more effectively than inhibiting AKT kinase activity.

Cells · Jun 19, 2024Peer-reviewedCancer Biology