Author

Jérémy Blavier

University of LiègeORCID 0000-0002-7055-6907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein structure· 1

Frequent Co-Authors

DAVID EDWIN HILLiD· 2 shared Jean‐Claude TwizereiD· 2 shared Julien OlivetiD· 2 shared Kerstin SpirohniD· 2 shared Marc VidaliD· 2 shared Michael A. CalderwoodiD· 2 shared Soon Gang ChoiiD· 2 shared Tong HaoiD· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

DAVID EDWIN HILLORCID

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2 papers

Recent·Most cited

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Julien Olivet, Jérémy Blavier, Simona Kostova, Sibusiso B. Maseko, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, , Erich E. Wanker

The paper presents an AI-guided pipeline for PPI drug discovery, identifying a SARS-CoV-2 inhibitor by combining experimental assays, machine learning, and virtual screening.

Molecular Systems Biology · Mar 11, 2024Peer-reviewedSystems Biology

Expanding the HDAC druggable landscape beyond enzymatic activity

Julien Olivet, Soon Gang Choi, Salvador Sierra, Tina M. O’Grady, Mario de la Fuente Revenga, Florent Laval, Vladimir V. Botchkarev, Christoph Gorgulla, Paul W. Coote, Jérémy Blavier, Ezekiel A. Geffken, Jimit Lakhani, Kijun Song, Zoe C. Yeoh, Bin Hu, , Marc Vidal

This paper identifies a non-enzymatic HDAC inhibitor with anti-tumor and anti-psychedelic effects, showing reduced gene modulation compared to enzymatic inhibitors.

bioRxiv · Dec 7, 2022 · PreprintMolecular Biology