Author

Sabrina Golusik

Max Delbrück Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Christopher SeckeriD· 3 shared Eduardo Silva RamosiD· 3 shared Erich E. WankeriD· 3 shared Martina Zenkner· 3 shared Philipp TrepteiD· 3 shared Stephanie Beetz· 3 shared DAVID EDWIN HILLiD· 2 shared Jean‐Claude TwizereiD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Christopher SeckerORCID

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Author profile →

3 papers

Recent·Most cited

HAP40 functions as a proteostasis regulator by controlling huntingtin interactions and its release into the extracellular space

Eduardo Silva Ramos, Annett Boeddrich, Christian Haenig, Philipp Trepte, Orchid Ammar, Christopher Secker, Oliver Popp, Andranik Ivanov, Brandon A. Keith, Rachel J. Harding, Franziska Schindler, Tomáš Koudelka, Leonard Roth, Nadine Scharek, Martina Zenkner, , Erich E. Wanker

This study identifies HAP40 as a proteostasis regulator that controls HTT interactions and mHTT secretion, impacting cellular homeostasis and pathobiology.

bioRxiv · Apr 1, 2026 · PreprintCell Biology

AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Philipp Trepte, Christopher Secker, Julien Olivet, Jérémy Blavier, Simona Kostova, Sibusiso B. Maseko, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, , Erich E. Wanker

The paper presents an AI-guided pipeline for PPI drug discovery, identifying a SARS-CoV-2 inhibitor by combining experimental assays, machine learning, and virtual screening.

Molecular Systems Biology · Mar 11, 2024Peer-reviewedSystems Biology

A quantitative mapping approach to identify direct interactions within complexomes

Philipp Trepte, Christopher Secker, Soon Gang Choi, Julien Olivet, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Marcel Sperling, Yang Wang, Tong Hao, Kerstin Spirohn, Jean‐Claude Twizere, Michael A. Calderwood, , Erich E. Wanker

The paper presents a framework combining two high-throughput interaction assays to distinguish direct from indirect protein interactions in complexes.

bioRxiv · Aug 25, 2021 · PreprintSystems Biology