Author

Marie A.C. Depuydt

Leiden UniversityORCID 0000-0002-7174-1952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Daniek KapteijniD· 2 shared Dominique P.V. de KleijniD· 2 shared Ernest Diez BenaventeiD· 2 shared Gary K. OwensiD· 2 shared Gerard PasterkampiD· 2 shared Gert Jan de BorstiD· 2 shared Hester M. den RuijteriD· 2 shared Koen H.M. PrangeiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Daniek KapteijnORCID

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2 papers

Recent·Most cited

Identification of endothelial-to-mesenchymal transition gene signatures in single-cell transcriptomics of human atherosclerotic tissue

Lotte Slenders, Marian Wesseling, Siting Wei, Arjan Boltjes, Daniek Kapteijn, Petra H. van der Kraak, Marie A.C. Depuydt, Koen H.M. Prange, Noortje A. M. van den Dungen, Ernest Diez Benavente, Dominique P.V. de Kleijn, Gert Jan de Borst, Menno P.J. de Winther, Hester M. den Ruijter, Gary K. Owens, , Michal Mokrý

The paper identifies gene signatures of endothelial-to-mesenchymal transition in human atherosclerotic tissue using combined in vitro and single-cell transcriptomic data.

Vascular Pharmacology · May 1, 2025Peer-reviewedMolecular Biology

Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques.

Ernest Diez Benavente, Santosh Karnewar, Michele F. Buono, Eloi Mili, Robin J. G. Hartman, Daniek Kapteijn, Lotte Slenders, Mark Daniels, Rédouane Aherrahrou, Tobias Reinberger, Barend M. Mol, Gert Jan de Borst, Dominique P.V. de Kleijn, Koen H.M. Prange, Marie A.C. Depuydt, , Hester M. den Ruijter

The paper identifies sex-stratified gene regulatory networks in atherosclerotic plaques, showing female plaques are enriched with myofibroblast-like smooth muscle cell networks.

Arteriosclerosis Thrombosis and Vascular Biology · Aug 17, 2023Peer-reviewedBioinformatics