The histone methyltransferase DOT1L regulates chromatin reorganization and gene expression during the postmeiotic differentiation of male germ cells
Mélina Blanco, Laïla El Khattabi, Clara Gobé, Marion Crespo, Manon Coulée, Alberto de la Iglesia, Côme Ialy‐Radio, Clémentine Lapoujade, Maëlle Givelet, Marion Delessard, Ivan Seller‐Corona, Kosuke Yamaguchi, Nadège Vernet, Fred van Leeuwen, Alban Lermine, , Julie Cocquet
This study shows that DOT1L regulates chromatin reorganization and gene expression in male germ cells, leading to fertility defects in its absence.
EMBO Reports · Apr 26, 2023Peer-reviewedMolecular Biology