Author

Jerry L. Chen

Boston UniversityORCID 0000-0002-7409-7859Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:imaging· 5 Organism:mouse· 5 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:Drosophila· 1

Frequent Co-Authors

Allison M. Ahrens· 4 shared Anderson CheniD· 2 shared Chang LiuiD· 2 shared Jelena PlatišaiD· 2 shared Lei TianiD· 2 shared Vincent A. PieriboneiD· 2 shared Xin YeiD· 2 shared Abed GhanbariiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersNeuroscience

Allison M. Ahrens

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Author profile →

6 papers

Recent·Most cited

DeepVID v2: Self-Supervised Denoising with Decoupled Spatiotemporal Enhancement for Low-Photon Voltage Imaging

Chang Liu, Jiayu Lu, Yicun Wu, Xin Ye, Allison M. Ahrens, Jelena Platiša, Vincent A. Pieribone, Jerry L. Chen, Lei Tian

DeepVID v2 improves low-photon voltage imaging by resolving spatial and temporal noise through self-supervised denoising with decoupled enhancement.

Neurophotonics · Oct 29, 2024Peer-reviewedNeuroscience

Perirhinal Cortex Learns A Predictive Map of The Task Environment

David G. Lee, Caroline A. McLachlan, Ramon Nogueira, O‐Sung Kwon, Alanna E. Carey, Garrett House, Gavin D. Lagani, Danielle LaMay, Stefano Fusi, Jerry L. Chen

The paper identifies neural signatures of a predictive map in perirhinal cortex during task learning in mice using tactile working memory tasks.

Nature Communications · Jul 2, 2024Peer-reviewedNeuroscience

High-Speed Low-Light In Vivo Two-Photon Voltage Imaging of Large Neuronal Populations

Jelena Platiša, Xin Ye, Allison M. Ahrens, Chang Liu, Anderson Chen, Ian G. Davison, Lei Tian, Vincent A. Pieribone, Jerry L. Chen

The paper develops tools for high-speed, low-light two-photon voltage imaging of large neuronal populations in awake mice, achieving stable imaging of over 100 neurons for an hour.

Nature Methods · Mar 27, 2023Peer-reviewedNeuroscience

Dense Functional and Molecular Readout of a Circuit Hub in Sensory Cortex

Cameron Condylis, Abed Ghanbari, Nikita Manjrekar, Karina Bistrong, Shenqin Yao, Zizhen Yao, Thuc Nghi Nguyen, Hongkui Zeng, Bosiljka Tasic, Jerry L. Chen

The paper combines calcium imaging and spatial transcriptomics to study functional and molecular properties of neuronal subclasses in the somatosensory cortex during a tactile working memory task.

Science · Jan 6, 2022Peer-reviewedNeuroscience

Flexible Simultaneous Mesoscale Two-Photon Imaging of Neural Activity at High Speeds

Mitchell Clough, Anderson Chen, Seong-Wook Park, Allison M. Ahrens, Jeffrey N. Stirman, Spencer L. Smith, Jerry L. Chen

This paper introduces a two-photon microscope that enables high-speed, simultaneous imaging of multiple brain regions in mice, demonstrating calcium activity measurement in sensorimotor cortex.

Nature Communications · Nov 17, 2021Peer-reviewedNeuroscience

jYCaMP: An optimized calcium indicator for two-photon imaging at fiber laser wavelengths

Manuel Alexander Mohr, Daniel Bushey, Abhi Aggarwal, Jonathan S. Marvin, Jeong Jun Kim, Emiliano Jimenez Marquez, Yajie Liang, Ronak H. Patel, John J Macklin, Chi-Yu Lee, Arthur Tsang, Getahun Tsegaye, Allison M. Ahrens, Jerry L. Chen, Douglas S. Kim, , Kaspar Podgorski

The paper introduces jYCaMP1, a calcium indicator optimized for two-photon imaging at wavelengths above 1000 nm, showing improved performance in mice and flies.

Nature Methods · May 25, 2020Peer-reviewedNeuroscience