Getahun Tsegaye

The paper develops two variants of a glutamate indicator with enhanced sensitivity and tailored deactivation rates for studying synaptic transmission in vivo.

This paper introduces two new far-red fluorescent GECIs, FR-GECO1a and FR-GECO1c, characterized for their Ca2+ sensitivity and performance in neuronal imaging.

The paper improves a GABA sensor, iGABASnFR2, with higher sensitivity and faster kinetics, enabling better in vivo imaging of GABAergic transmission.

This paper develops improved glutamate indicators with faster activation kinetics and better synaptic localization for imaging synaptic transmission in neurons.

The paper identifies a mutation that enhances the sensitivity of a fluorescent voltage indicator, improving its ability to detect both spiking and subthreshold voltage signals in multiple organisms.

The paper develops fast and sensitive GCaMP indicators for neural activity imaging, achieving ultra-fast kinetics and high sensitivity.

The paper describes engineering eFRET voltage indicators with positive-going fluorescence responses by modifying microbial rhodopsins.

The paper introduces jYCaMP1, a calcium indicator optimized for two-photon imaging at wavelengths above 1000 nm, showing improved performance in mice and flies.

Structure-guided mutagenesis of GCaMP6 plus neuron-based screening yields a jGCaMP7 family, each variant tuned to a different regime: single spikes, neurites and neuropil, or population imaging.

The paper introduces improved red calcium indicators that match the sensitivity of GFP-based indicators, enabling better in vivo neural activity imaging.