Lida Zoupi

This paper identifies FABP8/PMP2 as a defining feature of human and old-world monkey CNS myelin, revealing molecular heterogeneity in myelin sheaths and its role in cholesterol enrichment.

This study identifies reduced inhibition, bursting, and accelerated oscillations as drivers of early hippocampal hyperactivity in Alzheimer's disease using in vivo recordings in mice.

This study investigates the role of FMRP in oligodendrocyte maturation and myelination in human and rat models, finding shared defects in morphology and function.

PUFFFIN labels cell neighbourhoods using a fluorescent protein fusion, enabling tracking of cell interactions and profiling non-cell-autonomous responses in mammalian cells.

The paper identifies a conserved myelination mechanism in oligodendrocytes that forms paranodal bridges, enabling extended myelin sheaths along axons, which degenerate more frequently with age.

The paper compares remyelination by surviving and newly generated oligodendrocytes in MS, finding that newly generated cells produce more accurate and abundant myelin sheaths.

This paper investigates whether demyelination in multiple sclerosis leads to selective neurodegeneration of inhibitory interneurons and presents a rodent model to study this phenomenon.