Davide Gobbo

Cannabidiol reverses microglia activation and loss of parvalbumin interneurons and perineuronal nets in a mouse model of schizophrenia

This study shows that cannabidiol (CBD) reverses memory deficits and neuroinflammation in a mouse model of schizophrenia by targeting 5-HT1A and CB2 receptors.

Neuronal lysosome transfer to oligodendrocyte precursor cells: a novel mechanism of neuron-glia communication and its role in neurodegenerative disease

The paper identifies a novel neuron-glia communication mechanism where neurons transfer lysosomes to OPCs, linking this process to neurodegenerative disease progression.

Adenosine triggers early astrocyte reactivity that provokes microglial activation and drives the pathogenesis of sepsis-associated encephalopathy

This study shows that adenosine triggers early astrocyte reactivity in sepsis, leading to microglial activation and SAE pathogenesis.

Genetic ablation of GABAB receptors from oligodendrocyte precursor cells protects against demyelination in the mouse spinal cord

This study shows that removing GABAB receptors from oligodendrocyte precursor cells in mice protects against demyelination in spinal cord injury models.

Time-lapse Imaging of Microglial Activity and Astrocytic Calcium Signaling Reveals a Neuroprotective Effect of Cannabidiol in the Subacute Phase of Stroke

This study uses in vivo imaging to show that cannabidiol reduces microglial activation and protects neurons in the subacute phase of stroke.

Novel algorithms for improved detection and analysis of fluorescent signal fluctuations

The paper introduces two algorithms for detecting and analyzing fluorescent signal fluctuations, along with an interactive tool for their application.