Yan Liu

This study identifies species-specific differences in TNF-induced cell death mechanisms between human and mouse cells, highlighting discrepancies in RIPK1 and TRADD function that affect drug efficacy.

This paper shows mTORC1 regulates TNF-induced cell death by destabilizing complex I and promoting complex II formation, with implications for disease therapies.

The paper identifies a Smad4-loss-driven neutrophil-enriched subtype in prostate cancer models and shows that targeting epigenetic enzymes can suppress tumor growth.

This study identifies miR-544-3p as a regulator of arthritis pain by targeting FcγRI in DRG neurons, showing its potential as a therapeutic target.