Nanopore ReCappable Sequencing maps SARS-CoV-2 5' capping sites and provides new insights into the structure of sgRNAs
Camilla Ugolini, Logan Mulroney, Adrien Léger, Matteo Castelli, Elena Criscuolo, Maia Kavanagh Williamson, Andrew D. Davidson, Abdulaziz Almuqrin, Roberto Giambruno, Miten Jain, Gianmaria Frigè, Hugh E. Olsen, George Tzertzinis, Ira Schildkraut, Madalee G. Wulf, , Tommaso Leonardi
This study introduces NRCeq, a method to identify capped full-length SARS-CoV-2 transcripts, revealing new insights into sgRNA structure and expression.
Nucleic Acids Research · Feb 16, 2022Peer-reviewedGenomics