George Tzertzinis

The paper determines the structure of HPAMPD, a mollusk adenosine deaminase with nucleotide specificity, and shows how it binds the 5-monophosphate group of AMP through specific structural elements.

This study introduces NRCeq, a method to identify capped full-length SARS-CoV-2 transcripts, revealing new insights into sgRNA structure and expression.

ReCappable-seq identifies TSS for all RNA polymerases at single-nucleotide resolution, revealing novel TSS in nuclear and mitochondrial genomes and expanding understanding of non-Pol-II transcription.

The paper identifies high-confidence full-length human RNA isoform scaffolds using nanopore sequencing by improving 5' cap detection and 3' polyadenylation site identification.

This paper develops a high-temperature in vitro transcription method using thermostable T7 RNAP to produce low-immunogenicity mRNAs without post-synthesis purification.

This study characterizes the yeast DcpS enzyme's ability to decap long RNA transcripts and validates its use for enriching capped RNA through a tagging strategy.