Author

Sacha Ferdinandusse

Amsterdam University Medical CentersORCID 0000-0002-7738-5709Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Sabine A. FuchsiD· 2 shared Adam MyszczyszyniD· 1 shared Arif Ibrahim ArdisasmitaiD· 1 shared Ary MarseeiD· 1 shared Bart SpeeiD· 1 shared E. Gruber· 1 shared Edward E. S. NieuwenhuisiD· 1 shared Frédéric Maxime VaziD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Sabine A. FuchsORCID

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2 papers

Recent·Most cited

Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

Arif Ibrahim Ardisasmita, Indi P. Joore, N. Levy, Adam Myszczyszyn, Ary Marsee, Theo L. Sinnige, Jos P.N. Ruiter, Sacha Ferdinandusse, Oksana Y. Dudaryeva, E. Gruber, V. Daive, Riccardo Levato, Bart Spee, Monique M. A. Verstegen, Luc J. W. van der Laan, , Sabine A. Fuchs

This study develops hepatocyte-like liver organoids (HeLLOs) that closely mimic mature hepatocyte functions and outperform existing models in drug toxicity testing and disease modeling.

bioRxiv · Oct 29, 2024 · PreprintCell Biology

Tracer-based lipidomics identifies novel disease-specific biomarkers in mitochondrial β-oxidation disorders

Marit Schwantje, Signe Mosegaard, Suzan J. G. Knottnerus, Jan Bert van Klinken, Ronald J. A. Wanders, Henk van LENTHE, Jill Hermans, Lodewijk IJlst, Simone W. Denis, Yorrick R. J. Jaspers, Sabine A. Fuchs, Riekelt H. Houtkooper, Sacha Ferdinandusse, Frédéric Maxime Vaz

The paper uses tracer-based lipidomics to identify two new disease-specific biomarkers for mitochondrial β-oxidation disorders, revealing insights into lipid metabolism and potential diagnostic applications.

bioRxiv · Aug 31, 2023 · PreprintMolecular Biology