Author
Carnegie Mellon UniversityORCID 0000-0002-7882-6182Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Ghada Abdelhady, Qiao Su, Andrew Z. Wang…·Andreas R. Pfenning
The paper identifies cell-type-specific epigenetic signatures linked to neuronal vulnerability and longevity across placental mammals using epigenomics and AI.
Ashley R. Brown, Grant A Fox, Irene M. Kaplow…·Andreas R. Pfenning
The paper introduces WhAMPRA, an in vivo MPRA platform in mice, to assess tissue-specific regulatory functions of genetic variants and enhancers.
BaDoi N. Phan, Madelyn H. Ray, Xiangning Xue…·Ryan Wellington Logan
The paper uses single nuclei RNA-sequencing to identify striatal cell types in humans and rhesus macaques and finds molecular changes linked to opioid use disorder.
Gwyneth Welch, Carles A. Boix, Eloi Schmauch…·Li‐Huei Tsai
The paper identifies that DNA double strand breaks in neurons activate immune pathways, leading to microglia activation in neurodegeneration.
Jae-Hyun Yang, Patrick T. Griffin, Daniel L. Vera…·David A. Sinclair
The paper shows that inducing DNA breaks accelerates aging-related chromatin changes and loss of cell identity in mammals.