Christine A. Berryhill

Genetic activation of ERK2 recapitulates core neurodevelopmental features of Rasopathy syndromes in mice

This study shows that genetic activation of ERK2 in mice models key neurodevelopmental features of Rasopathy syndromes, including cognitive impairments and facial dysmorphology.

ZNF423 depletion induces the integrated stress response and represents a potential vulnerability in NF1-associated MPNST

This study shows ZNF423 depletion triggers the integrated stress response and sensitizes NF1-associated MPNST to chemotherapy, identifying it as a potential therapeutic target.

RIPK1 regulates beta-cell fate via actions on gene expression and kinase signaling in a mouse model of beta-cell self-reactivity

This study shows RIPK1 promotes beta-cell death in autoimmune diabetes by affecting gene expression and kinase signaling, suggesting it as a therapeutic target.

Characterization of Lysine Methylation During Neuronal Differentiation of LUHMES cells.

This study identifies changes in non-histone lysine methylation during neuronal differentiation of LUHMES cells using quantitative proteomics.

Quantitative analysis of non-histone lysine methylation sites and lysine demethylases in breast cancer cell lines

The paper quantifies non-histone lysine methylation sites and lysine demethylases in breast cancer cell lines using TMT labeling without antibody enrichment, identifying differentially abundant sites and enzymes.