Aram Megighian

Repellent olfactory cues influence the optomotor response modulation in Drosophila melanogaster

This study shows that repellent olfactory cues alter the optomotor response in Drosophila melanogaster when combined with optic flow stimulation.

A Syntaxin1A protein mutation drives sleep reduction in Drosophila

This study shows that a Syntaxin1A mutation in Drosophila reduces total sleep and causes fragmented sleep without affecting locomotor activity.

Targeting Neuromuscular Junction Regeneration is a Therapeutic Strategy in ALS

This study shows that targeting NMJ regeneration and CXCR4 can improve motor function and survival in ALS models.

Motor history influences behavioral strategy more than response outcome in Drosophila melanogaster

The paper investigates how motor history affects decision-making in Drosophila, finding that past motor activity influences strategy more than response outcome.

Low Intestinal Doses of Botulinum Neurotoxins types A and B favour infection by Salmonella and Shigella without the flaccid paralysis of botulism

The paper shows that low doses of Botulinum Neurotoxins A and B enter cholinergic neurons and promote Salmonella and Shigella infection without causing flaccid paralysis.

Optokinetic response in D. Melanogaster reveals the nature of common repellent odorants.

The paper tests how repellent and masking odorants affect the optokinetic response in Drosophila melanogaster during flight.

A heuristic underlies the search for relief in fruit flies

This study identifies a spatial heuristic used by fruit flies to avoid bitter taste, showing invertebrates use simplified decision strategies.

TDP-43 regulates the expression levels of Disc-large in skeletal muscles to promote the assemble of the neuromuscular synapses in Drosophila

This study shows TDP-43 promotes neuromuscular synapse formation in Drosophila by regulating Disc-large expression, with similar mechanisms observed in human ALS tissues.

Mechanisms of selection for the control of action in Drosophila melanogaster

This study investigates how Drosophila melanogaster responds to visual distractors during locomotion, revealing two distinct behavioral strategies related to action selection.