Krystine Garcia‐Mansfield

SF3B1 mutation generates novel peptides from long non-coding RNAs

The paper uses long-read sequencing to identify novel lncRNAs generated by SF3B1 mutation and shows they produce functional peptides linked to cancer prognosis.

A tRNA-derived small RNA orchestrates cardioprotection through distinct cell-type-specific mechanisms

This study identifies a tRNA-derived small RNA that reduces cardiac fibrosis and hypertrophy through cell-type-specific mechanisms in mouse and human cardiac cells.

Integrative synaptosome multi-omics reveals disrupted synapse organization and localized cryptic transcripts in C9ORF72-Frontotemporal Dementia

This study uses multi-omic profiling of synaptosomes to identify molecular changes in C9-FTD, revealing disrupted synaptic pathways and localized cryptic transcripts.

Serum metabolomics signatures after an acute bout of combined traditional or high-intensity tactical training in young males and females

This study compares serum metabolomics responses to traditional combined exercise and high-intensity tactical training in young adults, finding similar patterns but greater magnitude changes with traditional exercise.

Resolving Immune Lineage and Cell-State Heterogeneity in Human PBMCs via Mass Spectrometry-Based Single-Cell Proteomics

The paper develops a pipeline for protein-level cell annotation in human PBMCs using mass spectrometry-based single-cell proteomics and validates it on unsorted samples.