Julian R. Naglik

This study shows that Candida albicans promotes colorectal cancer progression through two mechanisms: a candidalysin-TG2-Hwp1 axis and TG2-independent epithelial plasticity and migration.

This study shows the IL-1 family is essential for mucosal defense against Candida albicans, preventing infection and dissemination, but its absence in neutropenic conditions leads to fatal systemic infection.

This study identifies IL-1RAP as a target for reducing eosinophilia in allergic fungal airway disease using a mouse model of chronic A. fumigatus exposure.

This study investigates how cells repair damage from the fungal toxin candidalysin compared to bacterial pore-forming toxins, finding distinct Ca2+-dependent mechanisms and roles for MEK and annexins.

The paper shows that bacterial metabolite HMB-PP activates human gut γδ T-cells to suppress fungal growth, but this mechanism is impaired in Crohn's disease.

This study investigates how Candida species influence oral cancer progression through miRNA regulation, showing C. albicans drives oncogenic pathways while C. parapsilosis affects metabolic processes.