Erin J. Cram

CrJAMs are transcriptional repressors of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

This study identifies CrJAM2 and CrJAM3 as transcriptional repressors of the MIA pathway in C. roseus, showing their repression is modulated by methyl JA treatment.

The single-PDZ domain protein TXBP-3 regulates contractility in the C. elegans spermatheca

This study identifies TXBP-3 as a regulator of contractility in C. elegans spermatheca by modulating CaMKII activity and actin fiber alignment.

PES-8 is required for Cytoskeletal Organization and Contractility in the C. elegans Spermatheca

This study identifies PES-8 as a regulator of cytoskeletal organization and calcium-mediated contractility in the C. elegans spermatheca, showing its essential role in oocyte transit.

A switch in collagen expression regulates cessation of distal tip cell migration in C. elegans

The paper identifies a collagen expression switch in C. elegans distal tip cells that regulates migration cessation during gonad development.

GOA-1 regulates spermathecal transits

This study identifies GOA-1 as a regulator of spermathecal transits in C. elegans and identifies 16 candidate interactors through proximity labeling and mass spectrometry.

Stage-specific transcriptomics of a leader cell reveals cell machineries driving collective invasion

The paper presents a stage-specific transcriptomic dataset of C. elegans distal tip cells, identifying molecular programs driving leader cell invasion and revealing new genes involved in this process.

On-demand delivery of fibulin-1 enables repeated basement membrane stretching

The paper shows that fibulin-1 is delivered on-demand to the basement membrane during stretching in C. elegans, maintaining its structure and enabling repeated organ expansion.

Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin

This study investigates how mechanical forces in C. elegans spermatheca are influenced by myosin activity, anatomy, and ovulation state, revealing that embryo presence and myosin activation affect tension distribution in actomyosin fibers and apical junctions.

Caenorhabditis elegans PIEZO Channel Coordinates Multiple Reproductive Tissues to Govern Ovulation

This study identifies PEZO-1 as critical for ovulation and fertilization in C. elegans by coordinating reproductive tissues through mechanical sensing and calcium signaling.

Addition of Multiple Introns to a Cas9 Gene Results in Dramatic Improvement in Efficiency for Generation of Gene Knockouts in Plants

This study shows that adding 13 introns to the Cas9 gene significantly improves gene knockout efficiency in plants.