Author

Michael R. Knopp

European Molecular Biology LaboratoryORCID 0000-0002-8218-3263Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:Arabidopsis· 1 Organism:E. coli· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Athanasios TypasiD· 2 shared Michael ZimmermanniD· 2 shared Mikhail M. SavitskiiD· 2 shared Alexandra KoumoutsiiD· 1 shared Amber Brauer-NikonowiD· 1 shared André MateusiD· 1 shared Askarbek N OrakoviD· 1 shared Célia V. RomãoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Athanasios TypasORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Personalized microbiotas (counter-)select for antibiotic resistant pathogens

Michael R. Knopp, Sarela García‐Santamarina, Lina Michel, Dimitrios Papagiannidis, Sophia David, Denise Medeiros Selegato, Joshua L. C. Wong, Nicolai Karcher, Gad M. Frankel, Michael Zimmermann, Mikhail M. Savitski, Athanasios Typas

This study identifies how personalized gut microbiotas influence the competitiveness of antibiotic-resistant pathogens through carbohydrate competition and specific genetic mutations.

bioRxiv · Apr 8, 2026 · PreprintMicrobiology

Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria

Elisabetta Cacace, Manuela Tietgen, Meike Steinhauer, André Mateus, Tilman G. Schultze, Marina Eckermann, Marco Galardini, Vallo Varik, Alexandra Koumoutsi, Jordan J. Parzeller, Federico Corona, Askarbek N Orakov, Michael R. Knopp, Amber Brauer-Nikonow, Peer Bork, , Stephan Göttig

This study identifies nitroxoline's broad antibacterial activity against Gram-negative bacteria, its mode of action involving metal homeostasis and outer membrane disruption, and resistance mechanisms across multiple species.

Nature Communications · Apr 22, 2025Peer-reviewedMicrobiology