Author

Marlène Dufresne

Centre National de la Recherche ScientifiqueORCID 0000-0002-8654-963XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alban Ricard· 1 shared Alexandre StellaiD· 1 shared Amélie V. VillardiD· 1 shared Anne CouvelardiD· 1 shared Benoît ThibaultiD· 1 shared Camille GuyoniD· 1 shared Carine JoffreiD· 1 shared Carine Valle· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alban Ricard

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Autophagy driven by VPS34 enables differentiated cell plasticity and cancer initiation

Fernanda Ramos‐Delgado, Hala Shalhoub, Camille Guyon, Charles Handschin, Pablo Cerapio-Arroyo, R. D’Angelo, N. Therville, Amélie V. Villard, Coralie Cayron, Carine Valle, Émeline Sarot, Nathalie Dusserre, Mickaël Di‐Luoffo, Vinciane Rebours, Anne Couvelard, , Julie Guillermet‐Guibert

This study shows that VPS34-driven autophagy restricts cancer initiation by preventing transdifferentiation and reducing oncogenic KRAS promotion in pancreatic acinar cells.

bioRxiv · May 2, 2025 · PreprintPathology

The intrinsically disordered region of the E3 ubiquitin ligase TRIP12 induces the formation of chromatin condensates and interferes with DNA damage response.

Claire Vargas, Manon Brunet, Alban Ricard, Damien Varry, Dorian Larrieu, Fernando Muzzopappa, Fabian Erdel, Guillaume Labrousse, Naïma Hanoun, Lætitia Ligat, Manon Farcé, Alexandre Stella, Odile Burlet‐Schiltz, Henrik Laurell, Nicolas Béry, , Jérôme Torrisani

This study shows TRIP12's intrinsically disordered region drives chromatin condensate formation, disrupting DNA damage response and genome accessibility.

bioRxiv · Sep 13, 2023 · PreprintMolecular Biology