Author

Prasad N. Paradkar

Commonwealth Scientific and Industrial Research OrganisationORCID 0000-0002-6553-2214Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Arabidopsis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Melissa J. KleiniD· 2 shared Adam J. López‐DenmaniD· 1 shared Amardeep S. DhilloniD· 1 shared Andrew N. ClarksoniD· 1 shared Anna B. BuchmaniD· 1 shared Antoine DufouriD· 1 shared Ashfaqul HoqueiD· 1 shared Carli L. Roulston· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

Melissa J. KleinORCID

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Author profile →

3 papers

Recent·Most cited

Australian Culex annulirostris mosquitoes are competent vectors for Japanese encephalitis virus genotype IV

Melissa J. Klein, Sarah A. Jackson, Willy W. Suen, Jean Payne, Darcy Beveridge, Mel Hargreaves, Donna Gillies, Jianning Wang, Kim R. Blasdell, Mike Dunn, Adam J. López‐Denman, Peter A. Durr, David T. Williams, Prasad N. Paradkar

This study shows Australian Cx. annulirostris mosquitoes are highly efficient vectors for JEV genotype IV, with 100% infection rate and 87% saliva positivity.

Emerging Microbes & Infections · Nov 12, 2024Peer-reviewedMicrobiology

N-Terminomic Changes of Neurons During Excitotoxicity Reveal Proteolytic Events Associated with Synaptic Dysfunctions and Inform Potential Targets for Neuroprotection

S. Sadia Ameen, Nane Griem‐Krey, Antoine Dufour, Mohammed Iqbal Hossain, Ashfaqul Hoque, Sharelle A. Sturgeon, Harshal H. Nandurkar, Dominik F. Draxler, Robert Lindsay Medcalf, Mohd Aizuddin Kamaruddin, Isabelle S. Lucet, Michael G. Leeming, Dazhi Liu, Amardeep S. Dhillon, Jet Phey Lim, , Heung‐Chin Cheng

The paper identifies proteolytic events in neurons during excitotoxicity using N-terminomics, revealing calpain-mediated cleavage of synaptic proteins and potential therapeutic targets for neuroprotection.

Molecular & Cellular Proteomics · Apr 6, 2023Peer-reviewedNeuroscience

Engineered resistance to Zika virus in transgenic Ae. aegypti expressing a polycistronic cluster of synthetic miRNAs

Anna B. Buchman, Stephanie Gamez, Ming Li, Igor A. Antoshechkin, Hsing-Han Li, Hsin‐Wei Wang, Chun‐Hong Chen, Melissa J. Klein, Jean‐Bernard Duchemin, Prasad N. Paradkar, Omar S. Akbari

This study generates Ae. aegypti mosquitoes engineered with synthetic miRNAs to reduce ZIKV infection, dissemination, and transmission.

Proceedings of the National Academy of Sciences · Feb 5, 2019Peer-reviewedSynthetic Biology