Katherine Ann Gallagher

VGLL3-centered network connects placental, vascular, and immune defects in preeclampsia

This study identifies VGLL3 as a key driver of preeclampsia by linking it to placental, vascular, and immune defects, showing its therapeutic potential through genetic and pharmacological inhibition.

A Transcriptomic Atlas of Healthy Human Skin Links Regional Identity to Inflammatory Disease.

This study creates a high-resolution single-cell atlas of healthy human skin, revealing region-specific transcriptional networks and their links to inflammatory diseases.

Multi-ancestry GWAS deciphers genetic architecture of abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

This study identifies 144 genetic loci associated with abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target through Mendelian Randomization and pre-clinical validation.

Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits

The paper integrates snATAC-seq and snRNA-seq data from human and rat skeletal muscle to identify cell types, regulatory elements, and SNPs associated with complex traits.