Author

Kemal Marc Akat

Rockefeller UniversityORCID 0000-0002-9012-3551Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Thomas TuschliD· 3 shared Aitor GarziaiD· 1 shared Alina MunteanuiD· 1 shared Altuna AkaliniD· 1 shared Andrea VenturaiD· 1 shared Anuoluwapo SopeyiniD· 1 shared Arlene HurleyiD· 1 shared Bing ShuiiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMolecular Biology

Thomas TuschlORCID

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3 papers

Recent·Most cited

Inducible and reversible inhibition of miRNA-mediated gene repression in vivo

Gaspare La Rocca, Bryan King, Bing Shui, Xiaoyi Li, Minsi Zhang, Kemal Marc Akat, Paul Ogrodowski, Chiara Mastroleo, Kevin Chen, Vincenzo Cavalieri, Yilun Ma, Viviana Anelli, Doron Betel, Joana Alves Vidigal, Thomas Tuschl, , Andrea Ventura

This study develops a genetic tool to reversibly inhibit miRNA-mediated gene repression in vivo and shows tissue-specific dependencies on miRNA function for homeostasis and regeneration.

eLife · Aug 31, 2021Peer-reviewedMolecular Biology

Detection of circulating extracellular mRNAs by modified small RNA-sequencing analysis

Kemal Marc Akat, Youngmin A. Lee, Arlene Hurley, Pavel S Morozov, Klaas E.A. Max, Miguel Brown, Kimberly A. Bogardus, Anuoluwapo Sopeyin, Kai M. Hildner, Thomas G. Diacovo, Markus Friedrich Neurath, Martin Borggrefe, Thomas Tuschl

This study improves detection of extracellular mRNAs using modified small RNA-sequencing, revealing their potential as biomarkers and showing increased resolution in disease states.

JCI Insight · Apr 11, 2019Peer-reviewedMolecular Biology

Deciphering human ribonucleoprotein regulatory networks

Neelanjan Mukherjee, Hans‐Hermann Wessels, Svetlana Lebedeva, Marcin Piotr Sajek, Mahsa Ghanbari, Aitor Garzia, Alina Munteanu, Dilmurat Yusuf, Thalia Andrea Farazi, Jessica I. Hoell, Kemal Marc Akat, Altuna Akalin, Thomas Tuschl, Uwe Ohler

The paper analyzes RBP-RNA interactions across 64 RBPs to identify regulatory modules and their functional roles in RNA metabolism and localization.

Nucleic Acids Research · Nov 26, 2018Peer-reviewedGenomics