Soma Dash

Vascular Patterning affects Intramembranous Ossification through HIF1α-Vegf Signaling

This study shows that Med23 in endothelial cells is critical for vascular patterning and intramembranous ossification, with HIF1α-Vegf signaling playing a key role in craniofacial development.

rRNA transcription is integral to liquid-liquid phase separation and maintenance of nucleolar structure

The paper shows that rRNA transcription by Pol I is essential for nucleolar structure and liquid-liquid phase separation in mouse embryos.

Dynamic regulation and requirement for ribosomal RNA transcription duringmammalian development

The paper shows that disruptions in Pol I rRNA transcription specifically affect craniofacial development by causing NCC apoptosis and craniofacial anomalies in mice.

Nucleolin loss-of-function leads to aberrant FGF signaling and craniofacial anomalies

This study shows that Nucleolin loss-of-function in zebrafish causes craniofacial anomalies by disrupting Fgf signaling and rRNA synthesis.