Annita Achilleos

NR6A1 is essential for neural crest cell specification, formation and survival

This study identifies NR6A1 as a critical regulator of mammalian neural crest cell specification, formation, and survival through loss-of-function experiments and multiomic analyses.

Dynamic regulation and requirement for ribosomal RNA transcription duringmammalian development

The paper shows that disruptions in Pol I rRNA transcription specifically affect craniofacial development by causing NCC apoptosis and craniofacial anomalies in mice.

Nr6a1 controls axially-restricted body elongation, segmentation, patterning and lineage allocation

This study identifies Nr6a1 as a master regulator of trunk-specific axial development in mice, controlling elongation, segmentation, and lineage allocation through Hox gene regulation and gene regulatory networks.