Jacob B. Geri

This study identifies specific residues in the YTHDF2 IDR that regulate m6A-dependent mRNA decay using base-editor screens.

This study uses fluorescence microscopy and compositional analysis to show that plasma membrane proteins and lipids segregate into protein-rich domains and protein-poor regions, suggesting functional segregation of membrane processes.

This paper introduces a method to globally profile protein-ligand binding affinities using photocatalytic labeling and proteomics, applicable to various ligand types and biological samples.

This study shows that C3aR1 on β cells improves β cell function and survival, especially in obesity and T2D, by enhancing insulin secretion and reducing cell death.

This study shows that high estrogen levels during the proestrus phase increase binge drinking in female mice via rapid nongenomic signaling at estrogen receptor alpha in the bed nucleus of the stria terminalis.

This paper introduces a photocatalytic method for drug target identification that improves signal-to-noise and enables detection of low-abundance targets.