Author

Mathilde Mathieu

Åbo Akademi UniversityORCID 0000-0002-9304-9692Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Johanna IvaskaiD· 3 shared Giorgio ScitaiD· 2 shared Hellyeh HamidiiD· 2 shared Alexandra Clément· 1 shared Ana‐Maria Lennon‐DuméniliD· 1 shared Antti A. MäkitieiD· 1 shared Christel GoudotiD· 1 shared Eliane PiaggioiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

Johanna IvaskaORCID

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3 papers

Recent·Most cited

Cell BiologyNature MaterialsPeer-reviewedFeb 20, 2026

Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer

Jasmin Kaivola, Karolina Punovuori, Megan R. Chastney…·Johanna Ivaska

This study shows that restoring mechanophenotype or targeting YAP/TAZ can reverse malignant properties of vocal fold cancer by reducing nuclear YAP and β-catenin levels.

6 citationstop 3%

humanproteomics

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Cell BiologybioRxivPreprintFeb 3, 2026

Leupaxin inhibits the durotaxis and mechanosensitivity of metastatic breast cancer cells

Mathilde Mathieu, Jouni Härkönen, Monika Vaitkevičiūtė…·Johanna Ivaska

This study shows that leupaxin inhibits durotaxis and mechanosensitivity in metastatic breast cancer cells by disrupting paxillin-FAK signaling.

DOI 10.64898/2026.02.03.703253

humanbulk RNA-seq

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ImmunologybioRxivPreprintJan 17, 2025

Macrophages restrict tumor permissiveness to immune infiltration by controlling local collagen topography through a Tcf4-Collagen3 fibrotic axis

Zoé Fusilier, Franck Simon, Isabel Calvente…·Hélène D. Moreau

This study shows that macrophages control collagen network topography via Tcf4-Collagen3 pathway, influencing immune cell infiltration in tumors.

4 citations

humanbulk RNA-seq

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