Ariel M. Pani

Understanding How Actomyosin Dynamics Drive Apical Constriction by Systematically Tagging and Mapping Actin-Binding Proteins

The paper systematically maps the localization of 49 actin-binding proteins during C. elegans gastrulation to understand their roles in apical constriction.

Engineering the C. elegans genome with a nested, self-excising selection cassette

This paper introduces a new genetic tool, NSEC, to improve genome engineering in C. elegans by enabling homozygous lines for essential genes before marker excision.

FGF diffusion is required for directed migration of postembryonic muscle progenitors in C. elegans

The paper shows that FGF diffusion is required for directed migration of C. elegans muscle progenitors, revealing FGF as a diffusible chemoattractant.

FGF-dependent, polarized SOS activity orchestrates directed migration of C. elegans muscle progenitors independently of canonical effectors in vivo

This study identifies FGF-dependent, polarized SOS activity as a mechanism for directing C. elegans muscle progenitor migration, independent of canonical RTK effectors.

A simple method to dramatically increase C. elegans germline microinjection efficiency

This paper introduces a paintbrush method that significantly increases C. elegans microinjection efficiency by improving injection speed and survival rates.

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans

The paper investigates how NHR-67 and Groucho regulate the switch between proliferative and invasive states in C. elegans uterine cells.

Visualizing the metazoan proliferation-terminal differentiation decision in vivo

The paper introduces a CDK sensor to distinguish cycling cells from terminally differentiated cells in C. elegans and zebrafish, revealing commitment points and stochasticity in cell cycle control.