Author
Yu-Chieh Chung
The Ohio State UniversityORCID 0000-0002-9430-8393Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2017-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author links5 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
CRISPR-FOIL: A Programmable CRISPR Tool to Engineer and Illuminate Chromatin Folding in Live Human Cells
Yu-Chieh Chung, Sydney Willey, Siou-Luan He…·Li‐Chun Tu
CRISPR-FOIL engineers chromatin loops and compaction in live human cells using CRISPR to visualize and manipulate chromatin structure, showing its potential for gene regulation and disease therapy.
DOI 10.64898/2026.08.09.743771 - Cell BiologyGenome biologyPeer-reviewed
Differential Regulation of Large-scale Chromosome Conformations in Osteoblasts and Osteosarcoma
Madhoolika Bisht, Yu-Chieh Chung, Siou-Luan He…·Li‐Chun Tu
The paper uses CRISPR-Sirius to visualize differences in large-scale chromosome conformations between osteoblasts and osteosarcoma cells, revealing regulatory mechanisms involving H3K27me3 and CTCF/cohesin.
- Cell BiologybioRxivPreprint
CRISPR-Based DNA Imaging in Living Cells Reveals Cell Cycle-Dependent Chromosome Dynamics
Hanhui Ma, Li-Chun Tu, Ardalan Naseri…·Thoru Pederson
The paper uses CRISPR-Sirius to track chromosomal loci dynamics in living cells and finds cell cycle-dependent changes in DNA contortion and movement.
DOI 10.1101/195966 - Cell BiologybioRxivPreprint
Reconstructing Spatial Transport Distributions In The Nuclear Pore Complex From 2D Images -- How Reliable Is It?
Li-Chun Tu, Maximiliaan Huisman, Yu-Chieh Chung…·David Grunwald
The paper evaluates the reliability of 3D-SPEED, a method that reconstructs spatial transport distributions in the nuclear pore complex from 2D images.
DOI 10.1101/145110