Author

John E. Mullinax

Moffitt Cancer CenterORCID 0000-0002-9596-6785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Abdessamad A. Youssfi· 1 shared Ahmad A. TarhiniiD· 1 shared Alex Alfaro· 1 shared Alexander R.A. AndersoniD· 1 shared Alyssa ObermayeriD· 1 shared Amod SarnaikiD· 1 shared Anthony Augello· 1 shared Austin Daniel NewsamiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Abdessamad A. Youssfi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Lymphoma response to chimeric antigen receptor T cell therapy is driven by endogenous tumor-reactive CD8⁺ T cells

Bachisio Ziccheddu, Constanza Savid-Frontera, Venu V.G. Saralamma, Chandler Gatenbee, Abdessamad A. Youssfi, Monika Chojnacka, Meghan A. Menges, Luis Cuadrado-Delgado, Michael A. Durante, John E. Mullinax, Keyla Reid, Julieta Abraham Miranda, Salvatore Corallo, Emily Merritt, W Greg Sawyer, , Frederick Lundry Locke

This study shows that durable CAR-T therapy in lymphoma requires cooperation with endogenous CD8 T cells, and tumors lacking MHC class I or CD58 resist treatment.

bioRxiv · Oct 27, 2026 · PreprintCancer Biology

BCL11B targeting in tumor CD8+ T cells amplifies anti-tumor response by blocking exhaustion while promoting stemness and cytotoxicity

Leonardo Silvane, Τόμας Ζελένκα, Divya Priyanka Talada, Valeriu Bogdan Cismasiu, Shamima Islam, Raghwendra P. Singh, Zefanias Ngove, Sayan Chakraborty, MacLean S. Hall, Jamie L. Blauvelt, Erika Adriana Eksioglu, Soraya Zorro Manrique, Joseph Johnson, Alyssa Obermayer, Alex Alfaro, , Dorina Avram

This paper shows that reducing BCL11B in CD8+ T cells enhances anti-tumor response by preventing exhaustion and boosting stemness and cytotoxicity.

bioRxiv · Aug 7, 2026 · PreprintImmunology