This study shows that targeting RBM39 with indisulam promotes natural killer cell activity and eradicates neuroblastoma regardless of cellular state plasticity.

Nature Communications · Sep 17, 2025Peer-reviewedCancer Biology

Conditional c-MYC activation in catecholaminergic cells drives distinct neuroendocrine tumors: neuroblastoma vs somatostatinoma

Tingting Wang, Lingling Liu, Jie Fang, Hongjian Jin, Sivaraman Natarajan, Heather Sheppard, Meifen Lu, Gregory H. Turner, Thomas Confer, Melissa D. Johnson, Jeffrey D. Steinberg, Larry Ha, Nour Yadak, Richa Jain, David J. Picketts, , Jun Yang

This study creates two mouse models with conditional c-MYC activation in specific cell types, leading to distinct neuroendocrine tumors resembling human neuroblastoma and somatostatinoma.

Cancer Research · Nov 12, 2024Peer-reviewedCancer Biology

Chronic Cognitive and Cerebrovascular Function Following Mild Traumatic Brain Injury in Rats

Daniel R. Griffiths, L. Matthew Law, Conor Young, Alberto E. Fuentes, Seth Truran, Nina Karamanova, Laura C. Bell, Gregory H. Turner, Hannah Emerson, Diego Mastroeni, Rayna J. Gonzales, Peter D. Reaven, C. Chad Quarles, Raymond Q. Migrino, Jonathan Lifshitz

This study investigates the long-term cognitive and cerebrovascular effects of mild traumatic brain injury in rats, finding chronic cognitive dysfunction and altered vascular reactivity.

bioRxiv · Jan 5, 2022 · PreprintNeuroscience