Author

Stefan Hoehme

Leipzig UniversityORCID 0000-0002-9716-9587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Alexander George FletcheriD· 3 shared Paul MackliniD· 3 shared Ahmadreza GhaffarizadehiD· 2 shared Alexander R.A. AndersoniD· 2 shared Andrea J. Hawkins-DaarudiD· 2 shared Carl KesselmaniD· 2 shared Daniel RudermaniD· 2 shared David B. AgusiD· 2 shared

Activity by Year

2016-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Alexander George FletcherORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transient suppression of the ECM1 gatekeeper is essential for HGF/c-MET-driven liver regeneration

Ye Yao, Yujia Li, Chenjun Huang, Jiayi Ma, Liang Xu, Stephanie D. Wolf, Julian Gilljam, Haifeng Zeng, Stefan Munker, Xioachun Cao-Ehlker, Ruochan Li, Bernhard Willibald Renz, Hanno Nieß, Seddik Hammad, Elisa Holstein, , Sai Wang

This study identifies ECM1 as a gatekeeper that transiently suppresses HGF activity during liver regeneration, enabling tissue repair through c-MET-ERK-MYC signaling.

bioRxiv · Jun 10, 2026 · PreprintCell Biology

Open Benchmarking for Cell-Based Multiscale Models: Lessons from a Community Initiative

Thaleia Ntiniakou, James M. Osborne, Jieling Zhao, Jules Dichamp, Nicolò Cogno, Randy W. Heiland, Kwabena Amponsah, Jiří Pešek, Tobias Duswald, Othmane Hayoun-Mya, Jack Jennings, Matteo Pedrazzi, Ryan Bournes, Marco Ruscone, Fergus Cooper, , Arnau Montagud

This paper presents a community-driven benchmarking initiative for cell-based multiscale models, highlighting variations in tool implementations and advocating for standardized benchmarks and interoperability.

bioRxiv · Jul 16, 2025 · PreprintSystems Biology

MultiCellDS: a standard and a community for sharing multicellular data

Samuel H. Friedman, Alexander R.A. Anderson, David M. Bortz, Alexander George Fletcher, Hermann B. Frieboes, Ahmadreza Ghaffarizadeh, David Robert Grimes, Andrea J. Hawkins-Daarud, Stefan Hoehme, Edwin F. Juarez, Carl Kesselman, Roeland M. H. Merks, Shannon M. Mumenthaler, Paul K. Newton, Kerri‐Ann Norton, , Paul Macklin

The paper introduces MultiCellDS, a standard and community-driven initiative for sharing multicellular data to enhance research in cell biology.

bioRxiv · Dec 9, 2016 · PreprintSystems Biology

MultiCellDS: a community-developed standard for curating microenvironment-dependent multicellular data

The paper introduces MultiCellDS, a standard for multicellular data curation, and presents MultiCellDB as a database to store associated data, enhancing data sharing and utility in biological and clinical research.

bioRxiv · Dec 8, 2016 · PreprintSystems Biology