Isabelle Tardieux

Pentachloropseudilin disrupts multiple steps of the Toxoplasma gondii lytic cycle, consistent with predicted multi-myosin engagement

This paper shows pentachloropseudilin disrupts multiple stages of the Toxoplasma gondii lytic cycle by interfering with different myosins, suggesting it as a tool for studying myosin functions and a potential antiparasitic strategy.

SARS-CoV-2 ORF9b exploits mitochondrial recruitment to TOMM70 for proteasomal protection and tunes inflammatory remodeling during lung infection

This study shows SARS-CoV-2 ORF9b uses TOMM70 to avoid proteasomal degradation, reduces inflammation, and is not essential for viral replication or lung pathology.