Stephanie L. Hickey

Gonadal PIP-seq reveals genes involved in germ cell development and sexual differentiation in sea lamprey ( Petromyzon marinus )

The paper uses PIP-seq to analyze gonadal cell transcriptomes in sea lamprey, identifying gene expression patterns associated with germ cell development and sexual differentiation.

Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential prior to implantation in the mouse

The paper shows Smad4 is not required before implantation but is essential for epiblast morphogenesis after implantation in mice.

OCT4 is expressed in extraembryonic endoderm stem (XEN) cell progenitors during somatic cell reprogramming

The paper shows that OCT4 expression during reprogramming leads to iXEN cell formation, and SKM alone can induce this process, suggesting a role for XEN in pluripotency establishment.

A network-based approach for isolating the chronic inflammation gene signatures underlying complex diseases towards finding new treatment opportunities

The paper presents a computational approach to identify gene signatures of chronic inflammation in complex diseases and prioritize drugs for new therapeutic opportunities.

Cortical Foxp2 supports behavioral flexibility and developmental dopamine D1 receptor expression

This study shows that cortical Foxp2 is essential for behavioral flexibility and dopamine D1 receptor expression, with effects on cell type composition and gene expression in the neonatal cortex.