Matilde Balbi

Recipient-driven metabolic and epigenetic remodeling of donor hematopoietic cells after transplantation in Fanconi Anemia.

This study shows that the FA recipient environment after HCT causes metabolic, redox, and epigenetic changes in donor-derived hematopoietic cells, even when donor chimerism is stable.

Therapeutic efficacy of hiMSC-derived Extracellular Vesicles from Serum-containing and Xeno-free media for osteoarthritis treatment

This study evaluates the therapeutic effects of hiEVs from different media in an OA mouse model, finding that xeno-free hiEVs reduce joint damage and promote cartilage repair.

miR-29a-3p and TGF-beta Axis in Fanconi Anemia: Mechanisms Driving Metabolic Dysfunction and Genome Stability

This study identifies miR-29a-3p as a regulator of metabolic dysfunction and genome stability in Fanconi anemia by modulating the PI3K/AKT and TGF-beta pathways.